Having commenced operations in 2006, Aquinox Pharmaceuticals Inc. is a privately-held pharmaceutical company developing targeted small molecule therapeutics for the treatment of cancer and inflammatory disease. The Company has a strong intellectual property portfolio and library of pre-clinical drug candidates that target a unique biochemical enzyme called "SHIP" (SH2-containing inositol phosphatase) which regulates the PI3 kinase (PI3K) pathway. Outstanding technology coupled with an exceptional management team and a recently completed US $14.5 million financing make it a very exciting time to seize this wonderful opportunity.

We are currently seeking a Research Associate in Analytical Chemistry. The successful candidate will be responsible for general analytical method development, including HPLC, LC-MS, GC and related methodologies.

Responsibilities will include, but are not limited to, the following activities:

• Design and execute scientific experiments with minimal supervision.
• Develop and validate analytical methods to support drug discovery.
• Perform in vitro ADME assays as requested, including metabolic stability, protein binding and CYP inhibition.
• Sample preparation for routine LC-MS/MS analysis.
• Maintain R&D laboratory notebook according to established guidelines.
• Data reduction and presentation.

To be successful in this role, you will have the following qualifications and experience:

• B.Sc. in Chemistry or related field with 5-10 years of experience or relevant Masters degree with 3-5 years experience.
• Knowledge of modern analytical techniques including GC, HPLC and MS.
• Strong computer skills, with a background in Chemstation.
• Effective communication skills, strong interpersonal and organizational skills.
• Ability to work independently as well as in a team environment is essential.

Interested candidates are invited to forward their resume and cover letters to careers@aqxpharma.com. Please use the title of the position as the subject line and indicate where you saw this posting. Aquinox would like to thank all interested applicants for their interest; however, only those chosen for an interview will be contacted.