Director, Clinical Operations

Aquinox Pharmaceuticals Inc. is a private, venture-backed, pharmaceutical company developing novel and targeted small molecule therapeutics for the treatment of inflammatory disease. The company has a strong intellectual property portfolio and library of drug candidates that target a unique biochemical enzyme called “SHIP1”, which regulates the PI3 kinase pathway. Aquinox recently completed two Phase IIa clinical studies for its lead clinical candidate, AQX-1125. The Company’s outstanding technology coupled with an exceptional team, strong financing and track record make it an excellent time to seize this exciting opportunity.


  • Leads the design and conduct of phase I and II clinical trials including drafting and amending clinical protocols, overseeing data collection for clinical trials, as well as analyzing and interpreting data
  • Directs and administers clinical development plans and budgets for clinical contracts
  • Oversees the activities of principal investigators including negotiating arrangements for conducting clinical trials
  • Identifies Key Opinion Leaders in related therapeutic areas and establishes relationships and collaborations as appropriate.
  • Prepares and writes reports required for Regulatory Submissions, coordinating with Regulatory Affairs as appropriate
  • Lead and monitor all internal and external staff and resources associated with clinical operations as well as CRO’s and vendors
  • Works closely with biostatistics to interpret and analyze clinical trial results and outcomes
  • Participates as member of management team in overall product development strategy development
  • Participate as a member of AQX project teams, ensuring clinical operational challenges and issues are proactively identified and clearly articulated
  • Oversees the monitoring of clinical trials, ensuring timelines and protocols are adhered to
  • Participate in clinical protocol design, and amendments, and review all related documents
  • Ensures GCP compliance as appropriate

Qualifications and Experience

  • BS/MS in Life Sciences and a minimum of 10 years experience in Clinical Research; minimum 5 years of directly related experience in a similar role
  • Preferred candidates will have a proven track record of diversified Clinical Operations/Development experience at the management level within a biopharmaceutical environment, overseeing all aspects of Clinical Operations.
  • Must be a seasoned leader with the demonstrated ability to contribute to all levels of clinical development – from managing details, to strategizing about clinical trial design, to participation in partnering discussions and due diligence, is essential
  • Demonstrated ability to analyze and interpret Clinical Trial Results
  • Previous experience overseeing clinical trials within Europe and the US is necessary, along with a working knowledge of the EMEA and FDA clinical/regulatory environment. Knowledge/experience with Asthma/COPD trials is preferred
  • A “make-it-happen” attitude, along with a strong commitment to teamwork, and initiative are required
  • Demonstrated management and leadership skills
  • Excellent judgment and decision making skills
  • Effective oral and written communication skills along with strong problem solving abilities
  • Effective organizational and negotiation skills


Interested candidates are invited to forward their resume and cover letter to

While we thank all applicants for their interest, only those chosen for an interview will be contacted.